According to Matthew Diffee’s book of unpublished New Yorker cartoons, The Rejection Collection, there are about 50 regular New Yorker cartoonists who submit 10 cartoons each week. That’s 500 cartoons vying for about 12 to 20 slots. That’s not counting submissions from cartoonists whose work appears in the magazine irregularly or the thousand or so weekly unsolicited submissions (which stand almost no chance of getting in).